Varaico: Literature-Extracted Genetic Variants

Gene:POLB
Variant:p.I174S
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POLB

NM_002690.3:p.I174S

Associated Papers

DNA Polymerase β Cancer-Associated Variant I260M Exhibits Nonspecific Selectivity toward the β-γ Bridging Group of the Incoming dNTP.

Alnajjar KS et al.

Biochemistry, 2017

Catalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment.

Klvaňa M et al.

Biochemistry, 2012

Hinge residue I174 is critical for proper dNTP selection by DNA polymerase beta.

Yamtich J et al.

Biochemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."