Varaico: Literature-Extracted Genetic Variants

Gene:POLB
Variant:p.M236L
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POLB

NM_002690.3:p.M236L

Associated Papers

The Activity of Natural Polymorphic Variants of Human DNA Polymerase β Having an Amino Acid Substitution in the Transferase Domain.

Kladova OA et al.

Cells, 2023

Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase β.

Eckenroth BE et al.

Biochemistry, 2017

Translesion DNA polymerases and cancer.

Makridakis NM et al.

Frontiers in Genetics, 2012

Systematic biochemical analysis of somatic missense mutations in DNA polymerase β found in prostate cancer reveal alteration of enzymatic function.

An CL et al.

Human Mutation, 2011

Genomic analysis of cancer tissue reveals that somatic mutations commonly occur in a specific motif.

Makridakis NM et al.

Human Mutation, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."