Associated Papers
Detection of Somatic Mutation in Exon 12 of DNA Polymerase β in Ovarian Cancer Tissue Samples
Khanra K et al.
Iranian Biomedical Journal, 2018
HeLa Cells Containing a Truncated Form of DNA Polymerase Beta are More Sensitized to Alkylating Agents than to Agents Inducing Oxidative Stress.
Khanra K et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2015
Substrate rescue of DNA polymerase β containing a catastrophic L22P mutation.
Kirby TW et al.
Biochemistry, 2014
Understanding the loss-of-function in a triple missense mutant of DNA polymerase β found in prostate cancer.
An C et al.
International Journal of Oncology, 2013
Structural changes in the hydrophobic hinge region adversely affect the activity and fidelity of the I260Q mutator DNA polymerase β.
Gridley CL et al.
Biochemistry, 2013
Systematic biochemical analysis of somatic missense mutations in DNA polymerase β found in prostate cancer reveal alteration of enzymatic function.
An CL et al.
Human Mutation, 2011
Loop II of DNA polymerase beta is important for discrimination during substrate binding.
Lin GC et al.
Dna Repair, 2009
The Asp285 variant of DNA polymerase beta extends mispaired primer termini via increased nucleotide binding.
Murphy DL et al.
Biochemistry, 2008
Loop II of DNA polymerase beta is important for polymerization activity and fidelity.
Lin GC et al.
Nucleic Acids Research, 2007
Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate.
Hamid S et al.
Biochemistry, 2005
Is there a link between DNA polymerase beta and cancer?
Starcevic D et al.
Cell Cycle (georgetown, Tex.), 2004
The D246V mutant of DNA polymerase beta misincorporates nucleotides: evidence for a role for the flexible loop in DNA positioning within the active site.
Dalal S et al.
The Journal of Biological Chemistry, 2004
The E249K mutator mutant of DNA polymerase beta extends mispaired termini.
Kosa JL et al.
The Journal of Biological Chemistry, 1999
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