Associated Papers
CRISPR Screens Identify POLB as a Synthetic Lethal Enhancer of PARP Inhibition Exclusively in BRCA-Mutated Tumors.
Lazarides K et al.
Molecular Cancer Therapeutics, 2025
Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis.
Koczor CA et al.
Cell Reports, 2021
Pol β gap filling, DNA ligation and substrate-product channeling during base excision repair opposite oxidized 5-methylcytosine modifications.
Çağlayan M
Dna Repair, 2020
The ligation of pol β mismatch insertion products governs the formation of promutagenic base excision DNA repair intermediates.
Çağlayan M
Nucleic Acids Research, 2020
Enhanced Activity of Variant DNA Polymerase β (D160G) Contributes to Cisplatin Therapy by Impeding the Efficiency of NER.
Wang M et al.
Molecular Cancer Research : Mcr, 2019
Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.
Fang Q et al.
Nucleic Acids Research, 2019
Crosstalk between mismatch repair and base excision repair in human gastric cancer.
Simonelli V et al.
Oncotarget, 2017
Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase β.
Eckenroth BE et al.
Biochemistry, 2017
Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity.
Kothandapani A et al.
Nucleic Acids Research, 2013
Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide.
Trivedi RN et al.
Molecular Pharmacology, 2008
DNA polymerase beta overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells.
Canitrot Y et al.
Nucleic Acids Research, 2004
The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity.
Sobol RW et al.
Nature, 2000
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