Varaico: Literature-Extracted Genetic Variants

Gene:POLB
Variant:p.Y271F
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POLB

NM_002690.3:p.Y271F

Associated Papers

How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.

Wu WJ et al.

Journal of the American Chemical Society, 2014

The E295K cancer variant of human polymerase β favors the mismatch conformational pathway during nucleotide selection.

Eckenroth BE et al.

The Journal of Biological Chemistry, 2013

Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.

Beard WA et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."