Associated Papers
Structural changes in the hydrophobic hinge region adversely affect the activity and fidelity of the I260Q mutator DNA polymerase β.
Gridley CL et al.
Biochemistry, 2013
Catalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment.
Klvaňa M et al.
Biochemistry, 2012
Systematic biochemical analysis of somatic missense mutations in DNA polymerase β found in prostate cancer reveal alteration of enzymatic function.
An CL et al.
Human Mutation, 2011
The Asp285 variant of DNA polymerase beta extends mispaired primer termini via increased nucleotide binding.
Murphy DL et al.
Biochemistry, 2008
Loop II of DNA polymerase beta is important for polymerization activity and fidelity.
Lin GC et al.
Nucleic Acids Research, 2007
Dynamic characterization of a DNA repair enzyme: NMR studies of [methyl-13C]methionine-labeled DNA polymerase beta.
Bose-Basu B et al.
Biochemistry, 2004
A DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability.
Shah AM et al.
Biochemistry, 2001
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