Associated Papers
Mutagenic ligation of polβ mismatch insertion products during 8-oxoG bypass by LIG1 and LIG3α at the downstream steps of base excision repair pathway.
Lee KM et al.
Biorxiv : the Preprint Server for Biology, 2024
History of DNA polymerase β X-ray crystallography.
Whitaker AM et al.
Dna Repair, 2020
The ligation of pol β mismatch insertion products governs the formation of promutagenic base excision DNA repair intermediates.
Çağlayan M
Nucleic Acids Research, 2020
Substrate-induced DNA polymerase β activation.
Beard WA et al.
The Journal of Biological Chemistry, 2014
Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase β.
Koag MC et al.
Journal of the American Chemical Society, 2014
The E295K cancer variant of human polymerase β favors the mismatch conformational pathway during nucleotide selection.
Eckenroth BE et al.
The Journal of Biological Chemistry, 2013
DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion.
Freudenthal BD et al.
Nucleic Acids Research, 2013
Minor groove interactions at the DNA polymerase beta active site modulate single-base deletion error rates.
Osheroff WP et al.
The Journal of Biological Chemistry, 2000
Base substitution specificity of DNA polymerase beta depends on interactions in the DNA minor groove.
Osheroff WP et al.
The Journal of Biological Chemistry, 1999
DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity.
Werneburg BG et al.
Biochemistry, 1996
Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.
Beard WA et al.
The Journal of Biological Chemistry, 1996
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