Varaico: Literature-Extracted Genetic Variants

Gene:POLB
Variant:p.H285D
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POLB

NM_002690.3:p.H285D

Associated Papers

The Role of Natural Polymorphic Variants of DNA Polymerase β in DNA Repair.

Kladova OA et al.

International Journal of Molecular Sciences, 2022

Catalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment.

Klvaňa M et al.

Biochemistry, 2012

A triad interaction in the fingers subdomain of DNA polymerase beta controls polymerase activity.

Murphy DL et al.

Journal of the American Chemical Society, 2011

The Asp285 variant of DNA polymerase beta extends mispaired primer termini via increased nucleotide binding.

Murphy DL et al.

Biochemistry, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."