Varaico: Literature-Extracted Genetic Variants

Gene:POLB
Variant:p.E295A
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POLB

NM_002690.3:p.E295A

Associated Papers

Substrate-induced DNA polymerase β activation.

Beard WA et al.

The Journal of Biological Chemistry, 2014

The E295K cancer variant of human polymerase β favors the mismatch conformational pathway during nucleotide selection.

Eckenroth BE et al.

The Journal of Biological Chemistry, 2013

Catalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment.

Klvaňa M et al.

Biochemistry, 2012

Unfavorable electrostatic and steric interactions in DNA polymerase β E295K mutant interfere with the enzyme's pathway.

Li Y et al.

Journal of the American Chemical Society, 2012

DNA polymerase beta catalytic efficiency mirrors the Asn279-dCTP H-bonding strength.

Martínek V et al.

Febs Letters, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."