Varaico: Literature-Extracted Genetic Variants

Gene:POLB
Variant:p.T304I
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POLB

NM_002690.3:p.T304I

Associated Papers

Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway.

Almohdar D et al.

Journal of Molecular Biology, 2024

Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.

Fang Q et al.

Nucleic Acids Research, 2019

Human POLB gene is mutated in high percentage of colorectal tumors.

Donigan KA et al.

The Journal of Biological Chemistry, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."