Associated Papers
A targeted next-generation sequencing panel for identification of clinically relevant mutation profiles in solid tumours.
Das K et al.
Scientific Reports, 2025
PolED: a manually curated database of functional studies of POLE and POLD1 variants reported in humans.
Tsarin L et al.
Database : the Journal of Biological Databases and Curation, 2025
Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.
Vanni I et al.
Journal of Translational Medicine, 2024
Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation.
Orzan F et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023
Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene.
Bappy MNI et al.
Genetics Research, 2022
POLE/POLD1 mutation in non-exonuclease domain matters for predicting efficacy of immune-checkpoint-inhibitor therapy.
Chen YX et al.
Clinical and Translational Medicine, 2021
Comprehensive Genomic and Transcriptomic Analysis of Three Synchronous Primary Tumours and a Recurrence from a Head and Neck Cancer Patient.
Bresadola L et al.
International Journal of Molecular Sciences, 2021
Identification of New Tumor-Related Gene Mutations in Chinese Gastrointestinal Stromal Tumors.
Feng Y et al.
Frontiers in Cell and Developmental Biology, 2021
Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians.
Yadav S et al.
Oncogene, 2020
Olaparib is effective for recurrent urothelial carcinoma with BRCA2 pathogenic germline mutation: first report on olaparib response in recurrent UC.
Yang H et al.
Therapeutic Advances in Medical Oncology, 2020
Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population.
Yao J et al.
Scientific Reports, 2019
Identification of somatic alterations in lipoma using whole exome sequencing.
Kanojia D et al.
Scientific Reports, 2019
Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy.
Limviphuvadh V et al.
Bmc Cancer, 2018
The catalytic subunit of DNA polymerase δ inhibits γTuRC activity and regulates Golgi-derived microtubules.
Shen Y et al.
Nature Communications, 2017
Association of DNA repair gene polymorphisms with response to cisplatin-based concurrent chemoradiotherapy in patients with cervical carcinoma.
Liu JH et al.
Dna Repair, 2016
A steroid metabolizing gene variant in a polyfactorial model improves risk prediction in a high incidence breast cancer population.
Jupe ER et al.
Bba Clinical, 2014
Combined genetic and nutritional risk models of triple negative breast cancer.
Lee E et al.
Nutrition and Cancer, 2014
Genetic polymorphisms of multiple DNA repair pathways impact age at diagnosis and TP53 mutations in breast cancer.
Smith TR et al.
Carcinogenesis, 2011
DNA replication fidelity and cancer.
Preston BD et al.
Seminars in Cancer Biology, 2010
Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.
Smith TR et al.
Carcinogenesis, 2008
Association of a missense single nucleotide polymorphism, Cys1367Arg of the WRN gene, with the risk of bone and soft tissue sarcomas in Japan.
Nakayama R et al.
Cancer Science, 2008
Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk.
Kohno T et al.
Carcinogenesis, 2006
Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation.
Weber F et al.
American Journal of Human Genetics, 2006
Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.
Wu X et al.
American Journal of Human Genetics, 2006
Genetic variation and willingness to participate in epidemiologic research: data from three studies.
Bhatti P et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2005
Association of amino acid substitution polymorphisms in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk.
Sakiyama T et al.
International Journal of Cancer, 2005
Nucleotide-excision repair and prostate cancer risk.
Lockett KL et al.
Cancer Letters, 2005
Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes.
Sigurdson AJ et al.
Bmc Cancer, 2004