Varaico: Literature-Extracted Genetic Variants

Gene:POLE
Variant:p.E545K
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POLE

NM_006231.4:p.E545K

Associated Papers

Gene actionability according to the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT) in No Specific Molecular Profile (NSMP) endometrial cancer.

Mastrantoni L et al.

Esmo Open, 2025

Molecular characteristics of advanced colorectal cancer and multi-hit PIK3CA mutations.

Yasin F et al.

The Oncologist, 2024

KRAS and PIK3CA mutations in colorectal adenocarcinomas correlate with aggressive histological features and behavior.

Jang S et al.

Human Pathology, 2017

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.

Gong J et al.

Oncotarget, 2017

Improved survival associated with somatic PIK3CA mutations in copy-number low endometrioid endometrial adenocarcinoma.

Lin DI

Oncology Letters, 2015

PIKing the type and pattern of PI3K pathway mutations in endometrioid endometrial carcinomas.

Marchiò C et al.

Gynecologic Oncology, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."