Varaico: Literature-Extracted Genetic Variants

Gene:POLE
Variant:p.P452S
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POLE

NM_006231.4:p.P452S

Associated Papers

The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway.

Tang M et al.

Cell Death & Disease, 2024

38238314 (PubMed )
Supplement: 41419_2023_6418_MOESM1_ESM.docx

Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas.

van de Geer WS et al.

Neuro-oncology Advances, 0

35047820 (PubMed )
Supplement: vdab177_suppl_supplementary_data.xlsx › Figure5
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