Varaico: Literature-Extracted Genetic Variants

Gene:POLE
Variant:p.F367C
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POLE

NM_006231.4:p.F367C

Associated Papers

Phenotypic POLE Variant Classification Identifies Patients Who May Have Favorable Prognosis and Benefit from Immunotherapy.

Keller-Evans RB et al.

The Journal of Molecular Diagnostics : Jmd, 2026

Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes.

Harrison TA et al.

Bmc Cancer, 2025

Comparison between a Luminex-based multiplex kit with a sequence-specific oligonucleotide probe and next-generation sequencing for the detection of POLE oncogenic mutations in endometrial cancer.

Kato MK et al.

Virchows Archiv : an International Journal of Pathology, 2025

Prognostic values of molecular subtypes and SWI/SNF protein expression in de-differentiated/undifferentiated endometrial carcinoma.

Shin CY et al.

Histopathology, 2025

39811899 (PubMed )
Supplement: HIS-86-1053-s001.xlsx › Table_S2

Functions, interactions and prognostic role of POLE: a bioinformatics analysis.

Carvajal-Veloza J et al.

Journal of Gynecologic Oncology, 2025

39575998 (PubMed )
Supplement: jgo-36-e45-s001.xls › jgo-36-e45-s001

Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.

Shah SM et al.

Cancer Research Communications, 2024

Validation and Clinical Application of ONCOaccuPanel for Targeted Next-Generation Sequencing of Solid Tumors.

Kim M et al.

Cancer Research and Treatment, 2023

Utility of molecular subtypes and genetic alterations for evaluating clinical outcomes in 1029 patients with endometrial cancer.

Asami Y et al.

British Journal of Cancer, 2023

A new strategy in molecular typing: the accuracy of an NGS panel for the molecular classification of endometrial cancers.

Li Y et al.

Annals of Translational Medicine, 2022

Ultra-mutated colorectal cancer patients with POLE driver mutations exhibit distinct clinical patterns.

Hu H et al.

Cancer Medicine, 2021

Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.

Zaidi SH et al.

Nature Communications, 2020

Interpretation of somatic POLE mutations in endometrial carcinoma.

León-Castillo A et al.

The Journal of Pathology, 2020

Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene.

Hino H et al.

Cancer Medicine, 2019

Endometrial Carcinomas with POLE Exonuclease Domain Mutations Have a Favorable Prognosis.

McConechy MK et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."