Associated Papers
Phenotypic POLE Variant Classification Identifies Patients Who May Have Favorable Prognosis and Benefit from Immunotherapy.
Keller-Evans RB et al.
The Journal of Molecular Diagnostics : Jmd, 2026
The clinical landscape of POLE-mutant colorectal cancer: a retrospective analysis of real-world outcome.
Xu T et al.
Bmc Medicine, 2026
Immune checkpoint inhibitors for POLE or POLD1 proofreading-deficient metastatic colorectal cancer.
Ambrosini M et al.
Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2024
Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.
Shah SM et al.
Cancer Research Communications, 2024
38282550 (PubMed )
Supplement: crc-23-0312-s07.xlsx › Supplementary_table_6
Molecular Profiling of Endometrial Cancer: An Exploratory Study in Aotearoa, New Zealand.
Henry CE et al.
Cancers, 2021
Endometrial cancer with a POLE mutation progresses frequently through the type I pathway despite its high-grade endometrioid morphology: a cohort study at a single institution in Japan.
Monsur M et al.
Medical Molecular Morphology, 2021
Patient-derived organoids reflect the genetic profile of endometrial tumors and predict patient prognosis.
Berg HF et al.
Communications Medicine, 2021
Clinical patterns and genomic profiling of recurrent 'ultra-low risk' endometrial cancer.
Stasenko M et al.
International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society, 2020
Interpretation of somatic POLE mutations in endometrial carcinoma.
León-Castillo A et al.
The Journal of Pathology, 2020
Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer.
Stasenko M et al.
Gynecologic Oncology, 2020
Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations.
Hatakeyama K et al.
Scientific Reports, 2018
Mutations in POLE and survival of colorectal cancer patients--link to disease stage and treatment.
Stenzinger A et al.
Cancer Medicine, 2014
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