Varaico: Literature-Extracted Genetic Variants

Gene:POLE
Variant:p.A19D
Back to variants list

POLE

NM_006231.4:p.A19D

Associated Papers

PolED: a manually curated database of functional studies of POLE and POLD1 variants reported in humans.

Tsarin L et al.

Database : the Journal of Biological Databases and Curation, 2025

41263451 (PubMed )
Supplement: baaf076_supplemental_files.zip › Supplementary_Table_S1.xlsx › Table_S3

Reduced mutation rate in exons due to differential mismatch repair.

Frigola J et al.

Nature Genetics, 2017

29106418 (PubMed )
Supplement: NIHMS74504-supplement-Supplementary_table_5.xlsx › Sample_level_results

The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes.

Poulos RC et al.

Nucleic Acids Research, 2017

28531315 (PubMed )
Supplement: gkx463_supp.zip › Supplementary_Table_S1B.xlsx › Supp_Table_1B
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."