Varaico: Literature-Extracted Genetic Variants

Gene:POLE3
Variant:p.V82A
Back to variants list

POLE3

NM_017443.5:p.V82A

Associated Papers

Understanding the co-evolutionary molecular mechanisms of resistance in the HIV-1 Gag and protease.

Marie V et al.

Journal of Biomolecular Structure & Dynamics, 2022

HIV-1 Gag mutations alone are sufficient to reduce darunavir susceptibility during virological failure to boosted PI therapy.

Blanch-Lombarte O et al.

The Journal of Antimicrobial Chemotherapy, 2020

Epistasis as a determinant of the HIV-1 protease's robustness to mutation.

Capel E et al.

Plos One, 2014

Heat shock protein 90AB1 and hyperthermia rescue infectivity of HIV with defective cores.

Joshi P et al.

Virology, 2013

Potential elucidation of a novel CTL epitope in HIV-1 protease by the protease inhibitor resistance mutation L90M.

Smidt W

Plos One, 2013

Interplay between single resistance-associated mutations in the HIV-1 protease and viral infectivity, protease activity, and inhibitor sensitivity.

Henderson GJ et al.

Antimicrobial Agents and Chemotherapy, 2012

Association of Gag cleavage sites to protease mutations and to virological response in HIV-1 treated patients.

Malet I et al.

The Journal of Infection, 2007

The influence of protease inhibitor resistance profiles on selection of HIV therapy in treatment-naive patients.

Turner D et al.

Antiviral Therapy, 2004

Catalytic efficiency and phenotype of HIV-1 proteases encoding single critical resistance substitutions.

Cabana M et al.

Virology, 2002

Interference between D30N and L90M in selection and development of protease inhibitor-resistant human immunodeficiency virus type 1.

Sugiura W et al.

Antimicrobial Agents and Chemotherapy, 2002

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."