Associated Papers
De novo serine biosynthesis is protective in mitochondrial disease.
Jackson CB et al.
Cell Reports, 2025
Activating AMPK improves pathological phenotypes due to mtDNA depletion.
Carvalho G et al.
The Febs Journal, 2025
Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function.
Singh B et al.
Cell Death & Disease, 2018
Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties.
Singh B et al.
Plos One, 2015
Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesis.
Singh KK et al.
Journal of Human Genetics, 2009
Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.
Wanrooij S et al.
Nucleic Acids Research, 2007
Inducible expression of a dominant negative DNA polymerase-gamma depletes mitochondrial DNA and produces a rho0 phenotype.
Jazayeri M et al.
The Journal of Biological Chemistry, 2003
In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells.
Spelbrink JN et al.
The Journal of Biological Chemistry, 2000
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