Varaico: Literature-Extracted Genetic Variants

Gene:POLH
Variant:p.D652A
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POLH

NM_006502.3:p.D652A

Associated Papers

Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation.

Moreno NC et al.

Nucleic Acids Research, 2026

Polymerase Eta Recruits FANCD2 to Common Fragile Sites to Maintain Genome Stability.

Niljikar M et al.

Biorxiv : the Preprint Server for Biology, 2025

DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation.

Moreno NC et al.

Biorxiv : the Preprint Server for Biology, 2024

Aberrant C-terminal domain of polymerase η targets the functional enzyme to the proteosomal degradation pathway.

Ahmed-Seghir S et al.

Dna Repair, 2015

Regulation of the specialized DNA polymerase eta: revisiting the biological relevance of its PCNA- and ubiquitin-binding motifs.

Despras E et al.

Environmental and Molecular Mutagenesis, 2012

DNA polymerase eta and chemotherapeutic agents.

Chou KM

Antioxidants & Redox Signaling, 2011

DNA polymerase eta, a key protein in translesion synthesis in human cells.

Cruet-Hennequart S et al.

Sub-cellular Biochemistry, 2010

Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta.

Bomar MG et al.

Embo Reports, 2007

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.

Bienko M et al.

Science (new York, N.y.), 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."