Varaico: Literature-Extracted Genetic Variants

Gene:POLK
Variant:p.R298H
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POLK

NM_016218.6:p.R298H

Associated Papers

Biochemical Activity of 17 Cancer-Associated Variants of DNA Polymerase Kappa Predicted by Electrostatic Properties.

Pathira Kankanamge LS et al.

Chemical Research in Toxicology, 2023

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.

Leong TL et al.

Oncogene, 2019

30348992 (PubMed )
Supplement: 41388_2018_536_MOESM6_ESM.xlsx › Germline_Variants

Characterization of Nine Cancer-Associated Variants in Human DNA Polymerase κ.

Antczak NM et al.

Chemical Research in Toxicology, 2018

Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.

Pritchard AL et al.

Plos One, 2018

29641532 (PubMed )
Supplement: pone.0194098.s003.xlsx › MultCaCa_DNArep

Six Germline Genetic Variations Impair the Translesion Synthesis Activity of Human DNA Polymerase κ.

Kim JK et al.

Chemical Research in Toxicology, 2016

Patterns and functional implications of rare germline variants across 12 cancer types.

Lu C et al.

Nature Communications, 2015

26689913 (PubMed )
Supplement: ncomms10086-s13.xlsx › supplementary_data_12
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."