Varaico: Literature-Extracted Genetic Variants

Gene:POLR2A
Variant:p.Q403K
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POLR2A

NM_000937.5:p.Q403K

Associated Papers

POLR2A Mutation is a Poor Prognostic Marker of Cerebellopontine Angle Meningioma.

Okano A et al.

Neurosurgery, 2024

Genetic characterization and mutational profiling of foramen magnum meningiomas: a multi-institutional study.

Hua L et al.

Journal of Neurosurgery, 2024

Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.

Youngblood MW et al.

Nature Communications, 2023

37805627 (PubMed )
Supplement: 41467_2023_41926_MOESM3_ESM.xlsx › SD1

Genomic Landscape of Meningiomas.

Wang JZ et al.

Advances in Experimental Medicine and Biology, 2023

NF2 Alteration/22q Loss Is Associated with Recurrence in WHO Grade 1 Sphenoid Wing Meningiomas.

Sakai Y et al.

Cancers, 2022

The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications.

Robert SM et al.

Journal of Neuro-oncology, 2022

Discovering the Molecular Landscape of Meningioma: The Struggle to Find New Therapeutic Targets.

Maggio I et al.

Diagnostics (basel, Switzerland), 2021

Type of bony involvement predicts genomic subgroup in sphenoid wing meningiomas.

Jin L et al.

Journal of Neuro-oncology, 2021

Meningioma: A Pathology Perspective.

Toland A et al.

Neurosurgery, 2021

Associations of pathological diagnosis and genetic abnormalities in meningiomas with the embryological origins of the meninges.

Okano A et al.

Scientific Reports, 2021

The spatial phenotype of genotypically distinct meningiomas demonstrate potential implications of the embryology of the meninges.

Fountain DM et al.

Oncogene, 2021

Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas.

González-Tablas M et al.

Frontiers in Oncology, 2021

34868937 (PubMed )
Supplement: DataSheet_1.docx

Molecular genetics of meningiomas.

Youngblood MW et al.

Handbook of Clinical Neurology, 2020

Emerging Medical Treatments for Meningioma in the Molecular Era.

Nigim F et al.

Biomedicines, 2018

Integrated genomic analyses of de novo pathways underlying atypical meningiomas.

Harmancı AS et al.

Nature Communications, 2017

Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas.

Clark VE et al.

Nature Genetics, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."