Varaico: Literature-Extracted Genetic Variants

Gene:PON1
Variant:p.L55M
Back to variants list

PON1

NM_000446.7:p.L55M

Associated Papers

A Pilot Study Exploring Paraoxonase-1 Tissue Protein Expression and Circulating Levels in Bladder Cancer.

Parada D et al.

Antioxidants (basel, Switzerland), 2026

Unveiling the Neuroprotective Effect of Paraoxonase 1 in Neurodegenerative Diseases Focusing on Alzheimer's Disease.

Ismail A et al.

Molecular Neurobiology, 2025

Newborn MTHFR rs1801133 Variant and Extremely Low Birth Weight: A Case-Control Study and Meta-Analysis.

Skulimowski B et al.

Genes, 2025

Impact of SNP Variants in PON-1 or UGT1A1 on Iron Chelation Therapy Outcomes and Zinc Status in Thalassemia Major Patients.

Lu MY et al.

Biological Trace Element Research, 2025

Paraoxonase 1 polymorphisms and their relationship with gastric cancer risk: a biochemical perspective on oxidative stress.

Najafi E et al.

Molecular Biology Reports, 2025

Investigating the role of the Pon1-rs854560 (L55M) SNP in colorectal Cancer susceptibility.

Wei X et al.

Journal of Cancer Research and Clinical Oncology, 2025

Association of CETP, APOA5, IL6, and PON1 Gene Variants with Dyslipidemia and Cardiovascular Risk in a Population from Cauca Department, Colombia.

Urbano-Cano AL et al.

Genes, 2025

Pon1 and Sult1a1 Polymorphisms and Breast Cancer Among Young Women in Brazil.

da Costa RSS et al.

Journal of Adolescent and Young Adult Oncology, 2025

Dantrolene is an HDL-associated paraoxonase-1 activator with immunosuppressive and atheroprotective properties.

Dedemadi AG et al.

Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids, 2025

Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma.

Kuras M et al.

Cancers, 2025

40075679 (PubMed )
Supplement: cancers-17-00832-s001.zip › Table_S5._SAAVs.xlsx › Table_S5A

Association of Paraoxonase-1 (p.L55M) and Paraoxonase-2 (p.S311C) polymorphisms with coronary artery disease in North Indian Punjabi population.

Bhat MA et al.

Frontiers in Endocrinology, 2025

Molecular Structure of Paraoxonase-1 and Its Modifications in Relation to Enzyme Activity and Biological Functions-A Comprehensive Review.

Lewoń-Mrozek D et al.

International Journal of Molecular Sciences, 2024

The importance of paraoxonase 1 activity in chronic kidney disease.

Samouilidou EC et al.

Renal Failure, 2024

Determination of selected oxysterol levels, oxidative stress, and macrophage activation indicators in children and adolescents with familial hypercholesterolemia.

Canbay E et al.

Lipids in Health and Disease, 2024

39538217 (PubMed )
Supplement: 12944_2024_2371_MOESM3_ESM.pdf

Regulation of Human Hydrolases and Its Implications in Pharmacokinetics and Pharmacodynamics.

Jung SM et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2024

A Case-Control Study Supports Genetic Contribution of the PON Gene Family in Obesity and Metabolic Dysfunction Associated Steatotic Liver Disease.

Van Dijck E et al.

Antioxidants (basel, Switzerland), 2024

PON1 rs662, rs854560 and TRIB1 rs17321515, rs2954029 Gene Polymorphisms Are Associated with Lipid Parameters in Patients with Unstable Angina.

Malinowski D et al.

Genes, 2024

Phospholipid metabolism-related genotypes of PLA2R1 and CERS4 contribute to nonobese MASLD.

Shao C et al.

Hepatology Communications, 2024

PON1, APOE and SDF-1 Gene Polymorphisms and Risk of Retinal Vein Occlusion: A Case-Control Study.

Ragkousis A et al.

Genes, 2024

ACE Phenotyping in Human Blood and Tissues: Revelation of ACE Outliers and Sex Differences in ACE Sialylation.

Enyedi EE et al.

Biomedicines, 2024

38790902 (PubMed )
Supplement: biomedicines-12-00940-s001.zip › biomedicines-2930173-supplementary.pdf

Association of PON1, APOE and SDF-1 Gene Polymorphisms with Treatment Response to Intravitreal Anti-VEGF Treatment in Patients with Retinal Vein Occlusion.

Ragkousis A et al.

Seminars in Ophthalmology, 2024

Single-Nucleotide Polymorphisms Associated with Mercury Levels and Neurological Symptoms: An Overview.

Perini JA et al.

Toxics, 2024

38535959 (PubMed )
Supplement: toxics-12-00226-s001.zip › toxics-2905208-supplementary.pdf

Role of PON1 L55M Gene Polymorphism in Parkinson's Disease among North Indian Population.

Kumar B et al.

Neurology India, 2024

The diversity and clinical implications of genetic variants influencing clopidogrel bioactivation and response in the Emirati population.

Khasawneh LQ et al.

Human Genomics, 2024

The Regulatory Variant -108C/T in the Promoter of Paraoxonase 1 (PON1) Gene has a More Important Role in Regulating PON1 Activity Compared to rs3735590 in 3'-UTR in Patients with Coronary Artery Disease.

Zargari M et al.

Advanced Biomedical Research, 2024

Structural Characteristics of PON1 with Leu55Met and Gln192Arg Variants Influencing Oxidative-Stress-Related Diseases: An Integrated Molecular Modeling and Dynamics Study.

M S et al.

Medicina (kaunas, Lithuania), 2023

The associations of PON1 and APOE polymorphisms with plasma lipid levels and the risk for late complications in type 2 diabetes patients.

Klen J et al.

Journal of Medical Biochemistry, 2023

The association of paraoxonase I gene polymorphisms Q192R (rs662) and L55M (rs854560) and its activity with metabolic syndrome components in fars ethnic group.

Marjani A et al.

Hormone Molecular Biology and Clinical Investigation, 2023

Augmented oxidative stress, accumulation of DNA damage and impaired DNA repair mechanisms in thrombotic primary antiphospholipid syndrome.

Pappa M et al.

Clinical Immunology (orlando, Fla.), 2023

Role of paraoxonase 1 activity and PON1 gene polymorphisms in sickle cell disease.

Menezes JF et al.

Scientific Reports, 2023

Proteomic Exploration of Paraoxonase 1 Function in Health and Disease.

Jakubowski H

International Journal of Molecular Sciences, 2023

Paraoxonase gene polymorphisms: Understanding the biochemical and genetic basis of coronary artery disease.

Nasreen FJ et al.

Journal of Taibah University Medical Sciences, 2023

Association between Genotype and the Glycemic Response to an Oral Glucose Tolerance Test: A Systematic Review.

Bayer S et al.

Nutrients, 2023

37049537 (PubMed )
Supplement: nutrients-15-01695-s001.zip › Table_S2.pdf

Association of APOE (rs429358 and rs7412) and PON1 (Q192R and L55M) Variants with Myocardial Infarction in the Pashtun Ethnic Population of Khyber Pakhtunkhwa, Pakistan.

Rahman N et al.

Genes, 2023

Do PON1-Q192R and PON1-L55M polymorphisms modify the effects of hypoxic training on paraoxonase and arylesterase activity?

Yigittürk O et al.

Journal of Sport and Health Science, 2023

Investigation of Paraoxonase-1 Genotype and Enzyme-Kinetic Parameters in the Context of Cognitive Impairment in Parkinson's Disease.

Petrič B et al.

Antioxidants (basel, Switzerland), 2023

A common genetic variation in paraoxonase 1 and risk of breast cancer: a literature review, meta-analysis, and in silico analysis.

Karimian M

Nucleosides, Nucleotides & Nucleic Acids, 2023

Decoding the genetic relationship between Alzheimer's disease and type 2 diabetes: potential risk variants and future direction for North Africa.

Boukhalfa W et al.

Frontiers in Aging Neuroscience, 2023

37342358 (PubMed )
Supplement: Table_2.XLSX › Table_2_SNPnexus_annotation

Plasma thrombin-activatable fibrinolysis inhibitor and the 1040C/T polymorphism are risk factors for diabetic kidney disease in Chinese patients with type 2 diabetes.

Huang Q et al.

Peerj, 2023

Role of Single Nucleotide Polymorphism L55M in the Paraoxonase 1 Gene as a Risk and Prognostic Factor in Acute Coronary Syndrome.

Doneva-Basheva KI et al.

Current Issues in Molecular Biology, 2022

Osteoprotegerin and MTHFR gene variations in rheumatoid arthritis: association with disease susceptibility and markers of subclinical atherosclerosis.

Arida A et al.

Scientific Reports, 2022

Genetic variants of PON1, GSTM1, GSTT1, and locus 9p21.3, and the risk for premature coronary artery disease in Yucatan, Mexico.

García-González I et al.

American Journal of Human Biology : the Official Journal of the Human Biology Council, 2022

Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts.

Dagli-Hernandez C et al.

Pharmacological Reports : Pr, 2022

Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.

Zarkasi KA et al.

International Journal of Environmental Research and Public Health, 2022

The effect of Paraoxonase gene polymorphisms and paraoxonase enzyme activity on Non-Hodgkin lymphoma.

Çınar E et al.

Nucleosides, Nucleotides & Nucleic Acids, 2022

1–50 of 586 papers
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."