Varaico: Literature-Extracted Genetic Variants

Gene:POR
Variant:p.E262G
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POR

NM_001395413.1:p.E262G

Associated Papers

Severe and prolonged cyclophosphamide-induced hepatotoxicity in a breast cancer patient carrying a CYP2B6*7 variant.

Ming Z et al.

Pharmacogenomics, 2019

Gene polymorphisms and contents of cytochrome P450s have only limited effects on metabolic activities in human liver microsomes.

Gao N et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2016

Investigation of the mechanisms underlying the differential effects of the K262R mutation of P450 2B6 on catalytic activity.

Bumpus NN et al.

Molecular Pharmacology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."