Varaico: Literature-Extracted Genetic Variants

Gene:POT1
Variant:p.Y242C
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POT1

NM_015450.3:p.Y242C

Associated Papers

Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.

Tausch E et al.

Haematologica, 2020

33054084 (PubMed )
Supplement: 2019.229161.TAUSCH_SUPPL.pdf

Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia.

Nadeu F et al.

Leukemia, 2018

28924241 (PubMed )
Supplement: leu2017291x1.pdf

Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis.

Gu P et al.

Oncogene, 2017

27869160 (PubMed )
Supplement: NIHMS818312-supplement-1.pdf

Mutations driving CLL and their evolution in progression and relapse.

Landau DA et al.

Nature, 2015

26466571 (PubMed )
Supplement: NIHMS715090-supplement-Supplementary_Table_3.xlsx › mutation_annotation_file_538_co
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."