Varaico: Literature-Extracted Genetic Variants

Gene:POU2F1
Variant:p.P283L
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POU2F1

NM_002697.4:p.P283L

Associated Papers

Insights Into Genetic Variations of the OCT1 Gene in Metformin Poor Responders Among Bangladeshi Type 2 Diabetic Patients.

Begum R et al.

Advances in Pharmacological and Pharmaceutical Sciences, 2025

The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics.

Yee SW et al.

Biorxiv : the Preprint Server for Biology, 2023

37333090 (PubMed )
Supplement: media-2.xlsx › S2_gnomAD_v2.1

Recent advance in the pharmacogenomics of human Solute Carrier Transporters (SLCs) in drug disposition.

Zhou F et al.

Advanced Drug Delivery Reviews, 2017

A phosphotyrosine switch regulates organic cation transporters.

Sprowl JA et al.

Nature Communications, 2016

Genetic polymorphisms of the organic cation transporter 1 gene (SLC22A1) within the Cape Admixed population of South Africa.

Du Plessis M et al.

Molecular Biology Reports, 2015

Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South Africa.

Jacobs C et al.

Genetics and Molecular Biology, 2014

Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacology.

Lozano E et al.

Biomed Research International, 2013

Transporter pharmacogenetics: transporter polymorphisms affect normal physiology, diseases, and pharmacotherapy.

Sissung TM et al.

Discovery Medicine, 2012

Serine racemase rs391300 G/A polymorphism influences the therapeutic efficacy of metformin in Chinese patients with diabetes mellitus type 2.

Dong M et al.

Clinical and Experimental Pharmacology & Physiology, 2011

Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.

Fahrmayr C et al.

Drug Metabolism Reviews, 2010

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

Nies AT et al.

Hepatology (baltimore, Md.), 2009

Japanese single nucleotide polymorphism database for 267 possible drug-related genes.

Iida A et al.

Cancer Science, 2006

[SNP collection, pharmacogenomics, and the future of drug therapy].

Iida A et al.

Gan to Kagaku Ryoho. Cancer & Chemotherapy, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."