Varaico: Literature-Extracted Genetic Variants

Gene:POU2F1
Variant:p.S408G
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POU2F1

NM_002697.4:p.S408G

Associated Papers

The impact of the solute carrier gene superfamily polymorphisms on tyrosine kinase inhibitors responses among chronic myeloid leukemia: A meta-analysis.

Thuy VT et al.

Leukemia Research, 2025

Insights Into Genetic Variations of the OCT1 Gene in Metformin Poor Responders Among Bangladeshi Type 2 Diabetic Patients.

Begum R et al.

Advances in Pharmacological and Pharmaceutical Sciences, 2025

Association of SLC22A1, SLC47A1, and KCNJ11 polymorphisms with efficacy and safety of metformin and sulfonylurea combination therapy in Egyptian patients with type 2 diabetes.

Ahmed A et al.

Research in Pharmaceutical Sciences, 2023

The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics.

Yee SW et al.

Biorxiv : the Preprint Server for Biology, 2023

37333090 (PubMed )
Supplement: media-2.xlsx › S3_Characterized

Role of human organic cation transporter-1 (OCT-1/SLC22A1) in modulating the response to metformin in patients with type 2 diabetes.

Kawoosa F et al.

Bmc Endocrine Disorders, 2022

The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition.

Zazuli Z et al.

International Journal of Molecular Sciences, 2020

Genetic polymorphisms of organic cation transporter 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes: A systematic review.

Mofo Mato EP et al.

Medicine, 2018

Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.

Lozano E et al.

Journal of Personalized Medicine, 2018

The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs.

van Leeuwen N et al.

Clinical Pharmacokinetics, 2013

Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacology.

Lozano E et al.

Biomed Research International, 2013

Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability - considerations for drug development.

Lai Y et al.

Expert Opinion on Drug Metabolism & Toxicology, 2012

Genetic analysis of OCT1 gene polymorphisms in an Indian population.

Umamaheswaran G et al.

Indian Journal of Human Genetics, 2011

Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin.

Shikata E et al.

Journal of Human Genetics, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."