Varaico: Literature-Extracted Genetic Variants

Gene:PPARG
Variant:p.P12A
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PPARG

NM_015869.5:p.P12A

Associated Papers

Genetic Associations of TCF7L2 (rs7903146) and PPARG (rs1801282) with Prediabetes in the Ethnic Kazakh Population.

Dyussupova A et al.

Diagnostics (basel, Switzerland), 2024

Putative protective genomic variation in the Lithuanian population.

Žukauskaitė G et al.

Genetics and Molecular Biology, 2024

Familial partial lipodystrophy resulting from loss-of-function PPARγ pathogenic variants: phenotypic, clinical, and genetic features.

Soares RMV et al.

Frontiers in Endocrinology, 2024

Decoding type 2 diabetes mellitus genetic risk variants in Pakistani Pashtun ethnic population using the nascent whole exome sequencing and MassARRAY genotyping: A case-control association study.

Jan A et al.

Plos One, 2023

Variable Expressivity and Allelic Heterogeneity in Type 2 Familial Partial Lipodystrophy: The p.(Thr528Met) LMNA Variant.

Araújo-Vilar D et al.

Journal of Clinical Medicine, 2021

Genetics and Clinical Characteristics of PPARγ Variant-Induced Diabetes in a Chinese Han Population.

Gong S et al.

Frontiers in Endocrinology, 2021

PPARG c.1347C>T polymorphism is associated with cancer susceptibility: from a case-control study to a meta-analysis.

Ding H et al.

Oncotarget, 2017

Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.

Lee H et al.

Nucleic Acids Research, 2017

Prospective functional classification of all possible missense variants in PPARG.

Majithia AR et al.

Nature Genetics, 2016

Proliferator-activated receptor gamma Pro12Ala interacts with the insulin receptor substrate 1 Gly972Arg and increase the risk of insulin resistance and diabetes in the mixed ancestry population from South Africa.

Vergotine Z et al.

Bmc Genetics, 2014

Variants in ABCB1, TGFB1, and XRCC1 genes and susceptibility to viral hepatitis A infection in Mexican Americans.

Zhang L et al.

Hepatology (baltimore, Md.), 2012

The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course.

Mwinyi J et al.

Ppar Research, 2012

Evolution of peroxisome proliferator-activated receptor gamma alternative splicing.

Dou T et al.

Frontiers in Bioscience (elite Edition), 2010

PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pro12Ala still remains as the strongest predictor.

Sanghera DK et al.

Metabolism: Clinical and Experimental, 2010

Association of PPARgamma allelic variation, osteoprotegerin and abdominal aortic aneurysm.

Moran CS et al.

Clinical Endocrinology, 2010

Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.

Breyer JP et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2009

Marker selection for genetic case-control association studies.

Pettersson FH et al.

Nature Protocols, 2009

Impact of the Pro12Ala polymorphism of the PPAR-Gamma 2 gene on metabolic and clinical characteristics in the Palestinian type 2 diabetic patients.

Ereqat S et al.

Ppar Research, 2009

Impact of peroxisome proliferator-activated receptors gamma and delta on adiposity in toddlers and preschoolers in the GENESIS Study.

Lagou V et al.

Obesity (silver Spring, Md.), 2008

Relationship between two sequence variations in the gene for peroxisome proliferator-activated receptor-gamma and plasma homocysteine concentration. Health in men study.

Golledge J et al.

Human Genetics, 2008

In vitro effect of PPAR-gamma2 Pro12Ala polymorphism on the deposition of Alzheimer's amyloid-beta peptides.

d'Abramo C et al.

Brain Research, 2007

Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease.

Schafmayer C et al.

Liver International : Official Journal of the International Association for the Study of the Liver, 2007

Human non-synonymous single nucleotide polymorphisms can influence ubiquitin-mediated protein degradation.

Savas S et al.

Omics : a Journal of Integrative Biology, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."