Varaico: Literature-Extracted Genetic Variants

Gene:PPARGC1A
Variant:p.G482S
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PPARGC1A

NM_013261.5:p.G482S

Associated Papers

Single-cell multi-omics data reveal heterogeneity in liver tissue microenvironment induced by hypertension.

Li H et al.

Molecular Therapy. Nucleic Acids, 2025

40989794 (PubMed )
Supplement: mmc9.pdf

β-Cell Mitochondrial Dysfunction: Underlying Mechanisms and Potential Therapeutic Strategies.

Darwish R et al.

Cells, 2025

The Distribution of Sport Performance Gene Variations Through COVID-19 Disease Severity.

Yenmis G et al.

Diagnostics (basel, Switzerland), 2025

Single nucleotide polymorphisms: Implications in the early diagnosis and targeted intervention of coronary microvascular dysfunction.

Tian D et al.

Genes & Diseases, 2025

A systematic review and functional in-silico analysis of genes and variants associated with amyotrophic lateral sclerosis.

Arreola-Aldape CA et al.

Frontiers in Neuroscience, 2025

40589786 (PubMed )
Supplement: Table_3.xlsx › Sheet1

Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.

Mao Y et al.

Frontiers in Nutrition, 2025

Association between the PPARGC1A Gly482Ser (rs8192678) polymorphism and endurance and power athlete status: a systematic review and meta-analysis.

Su W et al.

Frontiers in Physiology, 2025

Role of the PPARGC1A Gene and Its rs8192678 Polymorphism on Sport Performance, Aerobic Capacity, Muscle Adaptation and Metabolic Diseases: A Narrative Review.

Varillas-Delgado D

Genes, 2024

Influence of genetic polymorphism on sports talent performance versus non-athletes: a systematic review and meta-analysis.

Ferreira CP et al.

Bmc Sports Science, Medicine & Rehabilitation, 2024

Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.

Yang N et al.

Bmc Pediatrics, 2024

38310242 (PubMed )
Supplement: 12887_2024_4553_MOESM1_ESM.xlsx › trio.hg38.filter

Association of Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 Alpha Coding Variants with Hepatocellular Carcinoma Risk in the Moroccan Population: A Case-Control Study.

Tanouti IA et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2023

Comparative physiological anthropogeny: exploring molecular underpinnings of distinctly human phenotypes.

Vaill M et al.

Physiological Reviews, 2023

Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover.

Huang M et al.

Diabetologia, 2023

Association between Genotype and the Glycemic Response to an Oral Glucose Tolerance Test: A Systematic Review.

Bayer S et al.

Nutrients, 2023

37049537 (PubMed )
Supplement: nutrients-15-01695-s001.zip › Table_S1.pdf

The PPARGC1A Gly482Ser polymorphism is associated with elite long-distance running performance.

Hall ECR et al.

Journal of Sports Sciences, 2023

Association between the PPARGC1A Gly482Ser polymorphism and muscle fitness in Chinese schoolchildren.

Wei Q

Plos One, 2023

Association of rare PPARGC1A variants with Parkinson's disease risk.

Li LZ et al.

Journal of Human Genetics, 2022

Genetic Variants of VDR and PGC-1α Are Not Associated with the Risk of Endometriosis in Indian Women.

Beeram H et al.

Dna and Cell Biology, 2022

Genetics of long-distance runners and road cyclists-A systematic review with meta-analysis.

Konopka MJ et al.

Scandinavian Journal of Medicine & Science in Sports, 2022

35839336 (PubMed )
Supplement: SMS-32-1414-s001.docx

Gene Polymorphism and Total Genetic Score in Martial Arts Athletes with Different Athletic Qualifications.

Vostrikova A et al.

Genes, 2022

Transmission Distortion of MCT1 rs1049434 among Polish Elite Athletes.

Dzitkowska-Zabielska M et al.

Genes, 2022

Unraveling Gut Microbiota Signatures Associated with PPARD and PARGC1A Genetic Polymorphisms in a Healthy Population.

Bailén M et al.

Genes, 2022

Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure.

Panes JD et al.

Neural Regeneration Research, 2022

Molecular Dynamics Simulation and Essential Dynamics of Deleterious Proline 12 Alanine Single-Nucleotide Polymorphism in PPARγ2 Associated with Type 2 Diabetes, Cardiovascular Disease, and Nonalcoholic Fatty Liver Disease.

Taghvaei S et al.

Ppar Research, 2022

Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.

Schillemans T et al.

Frontiers in Physiology, 2022

Influence of Peroxisome Proliferator-Activated Receptor (PPAR)-gamma Coactivator (PGC)-1 alpha gene rs8192678 polymorphism by gender on different health-related parameters in healthy young adults.

Montes-de-Oca-García A et al.

Frontiers in Physiology, 2022

Case report: Whole-exome sequencing identifies a novel DES mutation (p. E434K) in a Chinese family with cardiomyopathy and sudden cardiac death.

Liu YX et al.

Frontiers in Cardiovascular Medicine, 2022

36277747 (PubMed )
Supplement: Data_Sheet_1.xls › Data_Sheet_1

Effects of PPARG and PPARGC1A gene polymorphisms on obesity markers.

Muntean C et al.

Frontiers in Public Health, 2022

Genotype Score for Iron Status Is Associated with Muscle Fiber Composition in Women.

Takaragawa M et al.

Genes, 2021

Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes.

Balberova OV et al.

Genes, 2021

PPARGC1A rs8192678 G>A polymorphism affects the severity of hepatic histological features and nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease.

Zhang RN et al.

World Journal of Gastroenterology, 2021

Genetic Basis for the Dominance of Israeli Long-Distance Runners of Ethiopian Origin.

Ben-Zaken S et al.

Journal of Strength and Conditioning Research, 2021

Associations among perfluorooctanesulfonic/perfluorooctanoic acid levels, nuclear receptor gene polymorphisms, and lipid levels in pregnant women in the Hokkaido study.

Kobayashi S et al.

Scientific Reports, 2021

Association of Genetic Variances in ADRB1 and PPARGC1a with Two-Kilometre Running Time-Trial Performance in Australian Football League Players: A Preliminary Study.

Jacob Y et al.

Sports (basel, Switzerland), 2021

Effects of Genetic Variation on Endurance Performance, Muscle Strength, and Injury Susceptibility in Sports: A Systematic Review.

Appel M et al.

Frontiers in Physiology, 2021

Computational Analysis of Gly482Ser Single-Nucleotide Polymorphism in PPARGC1A Gene Associated with CAD, NAFLD, T2DM, Obesity, Hypertension, and Metabolic Diseases.

Taghvaei S et al.

Ppar Research, 2021

Pharmacogenomics and Personalized Medicine in Type 2 Diabetes Mellitus: Potential Implications for Clinical Practice.

Venkatachalapathy P et al.

Pharmacogenomics and Personalized Medicine, 2021

Associations between nine candidate genetic polymorphisms with coronary heart disease : A meta-analysis.

Li Q et al.

Herz, 2020

Gene-environment interaction in chronic kidney disease among people with type 2 diabetes from The Malaysian Cohort project: a case-control study.

Ahmad N et al.

Diabetic Medicine : a Journal of the British Diabetic Association, 2020

Association of Candidate Gene Polymorphism with Metabolic Syndrome among Mongolian Subjects: A Case-Control Study.

Chuluun-Erdene A et al.

Medical Sciences (basel, Switzerland), 2020

PPARGC1A rs8192678 and NRF1 rs6949152 Polymorphisms Are Associated with Muscle Fiber Composition in Women.

Yvert T et al.

Genes, 2020

UCP2-866G/A Polymorphism is Associated with Prediabetes and Type 2 Diabetes.

Hou G et al.

Archives of Medical Research, 2020

PPARG (Pro12Ala) genetic variant and risk of T2DM: a systematic review and meta-analysis.

Sarhangi N et al.

Scientific Reports, 2020

32728045 (PubMed )
Supplement: 41598_2020_69363_MOESM12_ESM.pdf

Mitochondrial dysfunction: An emerging link in the pathophysiology of polycystic ovary syndrome.

Shukla P et al.

Mitochondrion, 2020

Association of the SH2B1 rs7359397 Gene Polymorphism with Steatosis Severity in Subjects with Obesity and Non-Alcoholic Fatty Liver Disease.

Perez-Diaz-Del-Campo N et al.

Nutrients, 2020

Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations.

Bhatta P et al.

Genomics, 2020

Genetic Variants in the Activation of the Brown-Like Adipocyte Pathway and the Risk for Severe Obesity.

da Fonseca ACP et al.

Obesity Facts, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."