Varaico: Literature-Extracted Genetic Variants

Gene:PPM1A
Variant:p.D146E
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PPM1A

NM_021003.5:p.D146E

Associated Papers

Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain.

Kumar JP et al.

The Journal of Biological Chemistry, 2024

39002674 (PubMed )
Supplement: mmc1.pdf

Role of active site arginine residues in substrate recognition by PPM1A.

Tani I et al.

Biochemical and Biophysical Research Communications, 2021

Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.

Waschbüsch D et al.

Embo Reports, 2021

34580980 (PubMed )
Supplement: EMBR-22-e52675-s001.pdf

Metal-dependent Ser/Thr protein phosphatase PPM family: Evolution, structures, diseases and inhibitors.

Kamada R et al.

Pharmacology & Therapeutics, 2020

A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.

Debnath S et al.

The Journal of Biological Chemistry, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."