Varaico: Literature-Extracted Genetic Variants

Gene:PPM1B
Variant:p.R179G
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PPM1B

NM_002706.6:p.R179G

Associated Papers

Magnesium-dependent-protein phosphatase 1B regulates the protein arginine methyltransferase 5 through the modulation of myosin phosphatase.

Keller I et al.

The Journal of Biological Chemistry, 2025

RBM10 regulates the tumorigenic potential of human cancer cells by modulating PPM1B and YBX1 activities.

Li Y et al.

Experimental Cell Research, 2024

The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity.

Tasdelen I et al.

The Biochemical Journal, 2013

Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2Cβ.

Yien YY et al.

The Journal of Biological Chemistry, 2012

Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation.

Lee YH et al.

The Journal of Biological Chemistry, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."