Varaico: Literature-Extracted Genetic Variants

Gene:PPP1CC
Variant:p.F227S
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PPP1CC

NM_002710.4:p.F227S

Associated Papers

The PARP1 selective inhibitor saruparib (AZD5305) elicits potent and durable antitumor activity in patient-derived BRCA1/2-associated cancer models.

Herencia-Ropero A et al.

Genome Medicine, 2024

39187844 (PubMed )
Supplement: 13073_2024_1370_MOESM3_ESM.xlsx › SNV

ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma.

Laverty DJ et al.

Nature Communications, 2024

Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.

Hynds RE et al.

Nature Communications, 2024

38821942 (PubMed )
Supplement: 41467_2024_47547_MOESM1_ESM.pdf

Establishment and Comprehensive Characterization of a Novel Preclinical Platform of Metastatic Retinoblastoma for Therapeutic Developments.

Zugbi S et al.

Investigative Ophthalmology & Visual Science, 2023

38117242 (PubMed )
Supplement: iovs-64-15-27_s002.xlsx › Supplementary_Table_2

Targeting genome integrity dysfunctions impedes metastatic potency in non-small cell lung cancer circulating tumor cell-derived explants.

Tayoun T et al.

Jci Insight, 2022

35511434 (PubMed )
Supplement: jciinsight-7-155804-s148.xlsx › All_mut_CDX

Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas.

Krishnan A et al.

Nature Communications, 2020

Molecular profiling of driver events in metastatic uveal melanoma.

Karlsson J et al.

Nature Communications, 2020

32313009 (PubMed )
Supplement: 41467_2020_15606_MOESM4_ESM.xlsx › All_variants

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor.

Murphy AJ et al.

Nature Communications, 2019

31862972 (PubMed )
Supplement: 41467_2019_13646_MOESM6_ESM.xlsx › WES_SNV

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma.

Lin W et al.

Nature Communications, 2018

30405107 (PubMed )
Supplement: 41467_2018_6889_MOESM3_ESM.xlsx › Sheet1
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."