Varaico: Literature-Extracted Genetic Variants

Gene:PPP1CC
Variant:p.P50R
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PPP1CC

NM_002710.4:p.P50R

Associated Papers

Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors.

Bonsor DA et al.

Nature Communications, 2026

41519889 (PubMed )
Supplement: 41467_2026_68319_MOESM3_ESM.pdf

Structural basis for SHOC2 modulation of RAS signalling.

Liau NPD et al.

Nature, 2022

Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.

Kwon JJ et al.

Nature, 2022

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