Varaico: Literature-Extracted Genetic Variants

Gene:PPP1R1B
Variant:p.T34A
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PPP1R1B

NM_032192.4:p.T34A

Associated Papers

A Homozygous Missense Variant in PPP1R1B/DARPP-32 Is Associated With Generalized Complex Dystonia.

Khan A et al.

Movement Disorders : Official Journal of the Movement Disorder Society, 2022

Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics.

Ferreira M et al.

Biochimica Et Biophysica Acta. Molecular Cell Research, 2019

DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration.

Alam SK et al.

Communications Biology, 2018

Lrrk2 and alpha-synuclein are co-regulated in rodent striatum.

Westerlund M et al.

Molecular and Cellular Neurosciences, 2008

Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action.

Zachariou V et al.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."