Varaico: Literature-Extracted Genetic Variants

Gene:PPP2CA
Variant:p.L199P
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PPP2CA

NM_002715.4:p.L199P

Associated Papers

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination.

Hu WP et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2025

Inactivation of mammalian target of rapamycin increases STAT1 nuclear content and transcriptional activity in alpha4- and protein phosphatase 2A-dependent fashion.

Fielhaber JA et al.

The Journal of Biological Chemistry, 2009

Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice.

Schild A et al.

Mechanisms of Development, 2006

Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice.

Kins S et al.

The Journal of Biological Chemistry, 2001

Functional expression of human PP2Ac in yeast permits the identification of novel C-terminal and dominant-negative mutant forms.

Evans DR et al.

The Journal of Biological Chemistry, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."