Varaico: Literature-Extracted Genetic Variants

Gene:PPP4C
Variant:p.D82A
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PPP4C

NM_002720.3:p.D82A

Associated Papers

ATM-SPARK: A GFP phase separation-based activity reporter of ATM.

Li X et al.

Science Advances, 2023

Dephosphorylation of DBC1 by Protein Phosphatase 4 Is Important for p53-Mediated Cellular Functions.

Lee J et al.

Molecules and Cells, 2015

Leucine methylation of protein phosphatase PP4C at C-terminal is critical for its cellular functions.

Lee J et al.

Biochemical and Biophysical Research Communications, 2014

Dephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks.

Lee DH et al.

Molecular Cell, 2014

Protein phosphatase PP4 is involved in NHEJ-mediated repair of DNA double-strand breaks.

Liu J et al.

Cell Cycle (georgetown, Tex.), 2012

Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response.

Lee DH et al.

The Embo Journal, 2012

A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination.

Lee DH et al.

Nature Structural & Molecular Biology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."