Associated Papers
PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK.
Cho E et al.
Cell Reports, 2021
PP6C hotspot mutations in melanoma display sensitivity to Aurora kinase inhibition.
Gold HL et al.
Molecular Cancer Research : Mcr, 2014
Melanoma-associated mutations in protein phosphatase 6 cause chromosome instability and DNA damage owing to dysregulated Aurora-A.
Hammond D et al.
Journal of Cell Science, 2013
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Krauthammer M et al.
Nature Genetics, 2012
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