Associated Papers
PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIPL to promote TNFα-mediated cell death.
Wu G et al.
Cell Death & Disease, 2022
PPP6C Negatively Regulates STING-Dependent Innate Immune Responses.
Ni G et al.
Mbio, 2020
PP6C hotspot mutations in melanoma display sensitivity to Aurora kinase inhibition.
Gold HL et al.
Molecular Cancer Research : Mcr, 2014
Melanoma-associated mutations in protein phosphatase 6 cause chromosome instability and DNA damage owing to dysregulated Aurora-A.
Hammond D et al.
Journal of Cell Science, 2013
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