Varaico: Literature-Extracted Genetic Variants

Gene:PPP6C
Variant:p.H92Y
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PPP6C

NM_001123355.2:p.H92Y

Associated Papers

PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK.

Cho E et al.

Cell Reports, 2021

Patterns of genomic evolution in advanced melanoma.

Birkeland E et al.

Nature Communications, 2018

29991680 (PubMed )
Supplement: 41467_2018_5063_MOESM7_ESM.xlsx › mutationsInDriverGenes_withDriv

Melanoma-associated mutations in protein phosphatase 6 cause chromosome instability and DNA damage owing to dysregulated Aurora-A.

Hammond D et al.

Journal of Cell Science, 2013

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Krauthammer M et al.

Nature Genetics, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."