Associated Papers
Understanding P-Rex regulation: structural breakthroughs and emerging perspectives.
Jones GD et al.
Biochemical Society Transactions, 2024
Tumorigenesis driven by the BRAFV600E oncoprotein requires secondary mutations that overcome its feedback inhibition of migration and invasion.
Gadal S et al.
Biorxiv : the Preprint Server for Biology, 2024
P-Rex1 and P-Rex2 RacGEFs and cancer.
Srijakotre N et al.
Biochemical Society Transactions, 2017
Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma.
Lissanu Deribe Y
Small Gtpases, 2016
Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Lissanu Deribe Y et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016
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