Associated Papers
Cryo-electron microscopy structure and analysis of the P-Rex1-Gβγ signaling scaffold.
Cash JN et al.
Science Advances, 2019
Somatic mutations of PREX2 gene in patients with hepatocellular carcinoma.
Yang MH et al.
Scientific Reports, 2019
P-Rex1 and P-Rex2 RacGEFs and cancer.
Srijakotre N et al.
Biochemical Society Transactions, 2017
Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations.
Horrigan SK et al.
Elife, 2017
Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Lissanu Deribe Y et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016
PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.
Mense SM et al.
Science Signaling, 2015
Melanoma genome sequencing reveals frequent PREX2 mutations.
Berger MF et al.
Nature, 2012
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