Associated Papers
Understanding P-Rex regulation: structural breakthroughs and emerging perspectives.
Jones GD et al.
Biochemical Society Transactions, 2024
Targeted DNA Sequencing of Cutaneous Melanoma Identifies Prognostic and Predictive Alterations.
Haugh AM et al.
Cancers, 2024
38611025 (PubMed )
Supplement: cancers-16-01347-s001.zip › cancers-2874995-supplementary.xlsx › TableS1
Clinical Practice of Targeted Capture Sequencing to Identify Actionable Alterations in Cholangiocarcinoma.
Ma K et al.
Cancers, 2022
36291846 (PubMed )
Supplement: cancers-14-05062-s001.zip › Supplementary_Tables.xlsx › Table_S3
Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1.
D'Andrea L et al.
Science Signaling, 2021
P-Rex1 and P-Rex2 RacGEFs and cancer.
Srijakotre N et al.
Biochemical Society Transactions, 2017
Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations.
Horrigan SK et al.
Elife, 2017
Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma.
Lissanu Deribe Y
Small Gtpases, 2016
Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Lissanu Deribe Y et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016
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