Varaico: Literature-Extracted Genetic Variants

Gene:PRIMPOL
Variant:p.D114A
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PRIMPOL

NM_152683.4:p.D114A

Associated Papers

RPA exhaustion activates SLFN11 to eliminate cells with heightened replication stress.

Stanage TH et al.

Nature Cell Biology, 2026

PrimPol Variant V102A with Altered Primase and Polymerase Activities.

Boldinova EO et al.

Journal of Molecular Biology, 2024

The role of catalytic and regulatory domains of human PrimPol in DNA binding and synthesis.

Boldinova EO et al.

Nucleic Acids Research, 2023

Identifying the role of PrimPol in TDF-induced toxicity and implications of its loss of function mutation in an HIV+ patient.

Duong VN et al.

Scientific Reports, 2020

hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity.

Wan L et al.

Embo Reports, 2013

PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication.

Bianchi J et al.

Molecular Cell, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."