Associated Papers
Impact of protein and small molecule interactions on kinase conformations.
Kugler V et al.
Elife, 2024
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.
Ferrarone JR et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024
LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.
Stein BD et al.
Cancer Discovery, 2023
STK11/LKB1 Loss of Function Is Associated with Global DNA Hypomethylation and S-Adenosyl-Methionine Depletion in Human Lung Adenocarcinoma.
Koenig MJ et al.
Cancer Research, 2021
Expression profiling of ubiquitin-related genes in LKB1 mutant lung adenocarcinoma.
Wang G et al.
Scientific Reports, 2018
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
Kim J et al.
Nature, 2017
LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT.
Kaufman JM et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2014
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