Associated Papers
The metabolic sensor AMPK: Twelve enzymes in one.
Smiles WJ et al.
Molecular Metabolism, 2024
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha.
Zhou Q et al.
Molecular Cell, 2022
Controversial molecular functions of CBS versus non-CBS domain variants of PRKAG2 in arrhythmia and cardiomyopathy: A case report and literature review.
Gong X et al.
Molecular Genetics & Genomic Medicine, 2022
ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress.
Guo QQ et al.
The Embo Journal, 2020
Human γ2-AMPK Mutations.
Yavari A et al.
Methods in Molecular Biology (clifton, N.j.), 2018
Molecular Pathogenesis of Familial Wolff-Parkinson-White Syndrome.
Miyamoto L
The Journal of Medical Investigation : Jmi, 2018
Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
Zhang CS et al.
Nature, 2017
Physiological Expression of AMPKγ2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.
Yang X et al.
The Journal of Biological Chemistry, 2016
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition.
Cordani M et al.
Molecular Oncology, 2016
Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation.
Pirkmajer S et al.
Diabetes, 2015
α-SNAP inhibits AMPK signaling to reduce mitochondrial biogenesis and dephosphorylates Thr172 in AMPKα in vitro.
Wang L et al.
Nature Communications, 2013
Structure of mammalian AMPK and its regulation by ADP.
Xiao B et al.
Nature, 2011
Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.
Hawley SA et al.
Cell Metabolism, 2010
Roles of the glycogen-binding domain and Snf4 in glucose inhibition of SNF1 protein kinase.
Momcilovic M et al.
The Journal of Biological Chemistry, 2008
Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.
Rudolph MJ et al.
Structure (london, England : 1993), 2007
Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome.
Davies JK et al.
American Journal of Physiology. Heart and Circulatory Physiology, 2006
N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity.
Zou L et al.
Circulation Research, 2005
Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site.
Adams J et al.
Protein Science : a Publication of the Protein Society, 2004
The AMP-activated protein kinase cascade--a unifying system for energy control.
Carling D
Trends in Biochemical Sciences, 2004
Functional analysis of mutations in the gamma 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome.
Daniel T et al.
The Journal of Biological Chemistry, 2002