Associated Papers
Nucleotide Substitution Biases in Related Cancer Driver Genes.
Khadre A et al.
International Journal of Molecular Sciences, 2025
ccfDNA analysis for the classification of adrenocortical adenomas.
Xu M et al.
Journal of Endocrinological Investigation, 2025
Molecular characterization of archival adrenal tumor tissue from patients with ACTH-independent Cushing syndrome.
Rege J et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2025
Diagnostic and therapeutic approaches to a case of pregnancy complicated by bilateral adrenocortical adenomas with primary aldosteronism and Cushing's syndrome.
Chen Y et al.
Endocrine, 2025
The molecular genetics of adrenal cushing.
Vaduva P et al.
Hormones (athens, Greece), 2024
Double CYP11B1/CYP11B2 Immunohistochemistry and Detection of KCNJ5 Mutations in Primary Aldosteronism.
Caroccia B et al.
The Journal of Clinical Endocrinology and Metabolism, 2024
Single-nucleus and spatial transcriptome reveal adrenal homeostasis in normal and tumoural adrenal glands.
Altieri B et al.
Clinical and Translational Medicine, 2024
Rare correlation of somatic PRKACA mutations with pregnancy-associated aldosterone- and cortisol-producing adenomas: a case report and literature review.
Lin J et al.
Bmc Endocrine Disorders, 2024
Steroids-producing nodules: a two-layered adrenocortical nodular structure as a precursor lesion of cortisol-producing adenoma.
Fukumoto T et al.
Ebiomedicine, 2024
Cardiovascular risk assessments in patients with cortisol-producing adenoma: impact of clinical features and genetic characteristics.
Watanabe D et al.
Heart and Vessels, 2024
Mosaic PRKACA duplication causing a novel and distinct phenotype of early-onset Cushing's syndrome and acral cutaneous mucinosis.
McGlacken-Byrne SM et al.
European Journal of Endocrinology, 2022
Cortisol-producing adenoma-related somatic mutations in unilateral primary aldosteronism with concurrent autonomous cortisol secretion: their prevalence and clinical characteristics.
Wu WC et al.
European Journal of Endocrinology, 2022
Targeted Mutational Analysis of Cortisol-Producing Adenomas.
Rege J et al.
The Journal of Clinical Endocrinology and Metabolism, 2022
Case Report: Primary Aldosteronism Due to Bilateral Aldosterone-Producing Micronodules With HISTALDO Classical and Contralateral Non-Classical Pathology.
Chen YJ et al.
Frontiers in Endocrinology, 2022
Mutational Profile and Potential Molecular Therapeutic Targets of Pheochromocytoma.
Ma X et al.
Frontiers in Endocrinology, 2022
Primary aldosteronism: Pathophysiological mechanisms of cell death and proliferation.
Tetti M et al.
Frontiers in Endocrinology, 2022
Disorders of the adrenal cortex: Genetic and molecular aspects.
Pitsava G et al.
Frontiers in Endocrinology, 2022
The cAMP-signaling cancers: Clinically-divergent disorders with a common central pathway.
Bolger GB
Frontiers in Endocrinology, 2022
Genotype-specific cortisol production associated with Cushing's syndrome adenoma with PRKACA mutations.
Baba R et al.
Molecular and Cellular Endocrinology, 2021
Clinical and Molecular Characteristics of PRKACA L206R Mutant Cortisol-Producing Adenomas in Korean Patients.
Jang I et al.
Endocrinology and Metabolism (seoul, Korea), 2021
Gαs-Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling.
Ramms DJ et al.
Pharmacological Reviews, 2021
Molecular Mechanisms of Functional Adrenocortical Adenoma and Carcinoma: Genetic Characterization and Intracellular Signaling Pathway.
Shimada H et al.
Biomedicines, 2021
Unravelling the Genetic Basis of Primary Aldosteronism.
Mourtzi N et al.
Nutrients, 2021
PKA Cα subunit mutation triggers caspase-dependent RIIβ subunit degradation via Ser114 phosphorylation.
Weigand I et al.
Science Advances, 2021
Genomic and sequence variants of protein kinase A regulatory subunit type 1β (PRKAR1B) in patients with adrenocortical disease and Cushing syndrome.
Drougat L et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2021
Genomic classification of benign adrenocortical lesions.
Faillot S et al.
Endocrine-related Cancer, 2021
Molecular Genetic and Genomic Alterations in Cushing's Syndrome and Primary Aldosteronism.
Kamilaris CDC et al.
Frontiers in Endocrinology, 2021
Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼.
Gao X et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2020
Molecular Basis of Primary Aldosteronism and Adrenal Cushing Syndrome.
Vaduva P et al.
Journal of the Endocrine Society, 2020
Adrenocortical tumorigenesis: Lessons from genetics.
Kamilaris CDC et al.
Best Practice & Research. Clinical Endocrinology & Metabolism, 2020
Somatic PRKACA Mutations: Association With Transition From Pituitary-Dependent to Adrenal-Dependent Cushing Syndrome.
Di Dalmazi G et al.
The Journal of Clinical Endocrinology and Metabolism, 2019
Molecular mechanisms in primary aldosteronism
De Sousa K et al.
Journal of Molecular Endocrinology, 2019
Pathogenic variants of DYNC2H1, KIAA0556, and PTPN11 associated with hypothalamic hamartoma.
Fujita A et al.
Neurology, 2019
Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks.
Nanba K et al.
Hypertension (dallas, Tex. : 1979), 2019
Alterations in Protein Kinase A Substrate Specificity as a Potential Cause of Cushing Syndrome.
Bathon K et al.
Endocrinology, 2019
Genetics of Cushing's Syndrome.
Hernández-Ramírez LC et al.
Endocrinology and Metabolism Clinics of North America, 2018
Kinetics and inhibition studies of the L205R mutant of cAMP-dependent protein kinase involved in Cushing's syndrome.
Luzi NM et al.
Febs Open Bio, 2018
Genetics of tumors of the adrenal cortex.
Bonnet-Serrano F et al.
Endocrine-related Cancer, 2018
Clinical Characteristics of Aldosterone- and Cortisol-Coproducing Adrenal Adenoma in Primary Aldosteronism.
Tang L et al.
International Journal of Endocrinology, 2018
Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors.
Tschida BR et al.
Cancer Research, 2017
Histopathological and genetic characterization of aldosterone-producing adenomas with concurrent subclinical cortisol hypersecretion: a case series.
Fallo F et al.
Endocrine, 2017
Lipofuscin Accumulation in Cortisol-Producing Adenomas With and Without PRKACA Mutations.
Angelousi A et al.
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, 2017
Microinsertions in PRKACA cause activation of the protein kinase A pathway in cardiac myxoma.
Tseng IC et al.
The Journal of Pathology, 2017
Mechanisms of Aberrant PKA Activation by Cα Subunit Mutations.
Calebiro D et al.
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, 2017
Clinical characteristics of PRKACA mutations in Chinese patients with adrenal lesions: a single-centre study.
Li X et al.
Clinical Endocrinology, 2016
Genetic Landscape of Sporadic Unilateral Adrenocortical Adenomas Without PRKACA p.Leu206Arg Mutation.
Ronchi CL et al.
The Journal of Clinical Endocrinology and Metabolism, 2016