Varaico: Literature-Extracted Genetic Variants

Gene:PRKACA
Variant:p.W197R
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PRKACA

NM_002730.4:p.W197R

Associated Papers

Protein kinase A is a dependent factor and therapeutic target in mouse models of fibrous dysplasia.

Liu Z et al.

Nature Communications, 2025

Molecular characterization of archival adrenal tumor tissue from patients with ACTH-independent Cushing syndrome.

Rege J et al.

The Journal of Steroid Biochemistry and Molecular Biology, 2025

Characterisation of a GNAS variant linked to cortisol-producing adrenocortical adenoma.

Jamaluddin A et al.

Endocrine Oncology (bristol, England), 2025

Comprehensive next-generation profiling of clonal hematopoiesis in cancer patients using paired tumor-blood sequencing for guiding personalized therapies.

Li Z et al.

Clinical and Translational Medicine, 2020

33252848 (PubMed )
Supplement: CTM2-10-e222-s003.xlsx › Sheet1

Alterations in Protein Kinase A Substrate Specificity as a Potential Cause of Cushing Syndrome.

Bathon K et al.

Endocrinology, 2019

Genetics of tumors of the adrenal cortex.

Bonnet-Serrano F et al.

Endocrine-related Cancer, 2018

Microinsertions in PRKACA cause activation of the protein kinase A pathway in cardiac myxoma.

Tseng IC et al.

The Journal of Pathology, 2017

Genetic Landscape of Sporadic Unilateral Adrenocortical Adenomas Without PRKACA p.Leu206Arg Mutation.

Ronchi CL et al.

The Journal of Clinical Endocrinology and Metabolism, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."