Associated Papers
The chordoid glioma PRKCA D463H mutation is a kinase inactive, gain-of-function allele that induces early-onset chondrosarcoma in mice.
Calleja V et al.
Science Signaling, 2025
A Catalytically Inactive Protein Kinase C alpha Mutation Drives Chordoid Glioma by Pathway Rewiring.
Bellamy C et al.
Biorxiv : the Preprint Server for Biology, 2025
Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt.
Gleason CE et al.
Journal of Cell Science, 2019
A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas.
Rosenberg S et al.
Nature Communications, 2018
29915258 (PubMed )
Supplement: 41467_2018_4622_MOESM2_ESM.pdf
A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle.
Goode B et al.
Nature Communications, 2018
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