Varaico: Literature-Extracted Genetic Variants

Gene:PRKCA
Variant:p.D463A
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PRKCA

NM_002737.3:p.D463A

Associated Papers

The complexities of PKCα signaling in cancer.

Black AR et al.

Advances in Biological Regulation, 2021

A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas.

Rosenberg S et al.

Nature Communications, 2018

29915258 (PubMed )
Supplement: 41467_2018_4622_MOESM2_ESM.pdf

A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle.

Goode B et al.

Nature Communications, 2018

PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.

Cameron AJ et al.

Nature Structural & Molecular Biology, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."