Varaico: Literature-Extracted Genetic Variants

Gene:PRKCA
Variant:p.D481E
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PRKCA

NM_002737.3:p.D481E

Associated Papers

Modulating PKCα Activity to Target Wnt/β-Catenin Signaling in Colon Cancer.

Dupasquier S et al.

Cancers, 2019

A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle.

Goode B et al.

Nature Communications, 2018

29476136 (PubMed )
Supplement: 41467_2018_2826_MOESM5_ESM.xlsx › Table_S5

Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor.

Newton AC et al.

Trends in Pharmacological Sciences, 2017

Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor.

Antal CE et al.

Cell, 2015

Mechanisms of regulation of phospholipase D1 by protein kinase Calpha.

Hu T et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."