Varaico: Literature-Extracted Genetic Variants

Gene:PRKCB
Variant:p.K371R
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PRKCB

NM_002738.7:p.K371R

Associated Papers

C-spine mutations of protein kinase C and Akt as a novel generalizable approach to create stable pseudokinases.

Hodapp SJ et al.

The Journal of Biological Chemistry, 2025

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.

Baffi TR et al.

Science Signaling, 2021

Protein Kinase C Quality Control by Phosphatase PHLPP1 Unveils Loss-of-Function Mechanism in Cancer.

Baffi TR et al.

Molecular Cell, 2019

Regulation of receptor-mediated protein kinase C membrane trafficking by autophosphorylation.

Feng X et al.

The Journal of Biological Chemistry, 2000

The hydrophobic phosphorylation motif of conventional protein kinase C is regulated by autophosphorylation.

Behn-Krappa A et al.

Current Biology : Cb, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."